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Ibuprofen, meanwhile, can cause dyspepsia, gastric erosion, and peptic ulceration, particularly with prolonged use or in patients with risk factors such as advanced age, previous peptic ulcer disease, or concurrent use of corticosteroids or anticoagulants

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Enhance skin hydration , reducing dryness and irritation

Working solutions and standard mixtures were subsequently prepared by dilution with ACN to the desired concentrations, with all final dilutions performed using an ACN/water mixture (9:1, v/v)